Mr. Raman, a 54-year-old man was brought to the emergency department with unconscious level and increased respiratory rate: Biochemistry Assignment, UTHM, Malaysia
| University | Universiti Tun Hussein Onn Malaysia (UTHM) |
| Subject | Biochemistry |
Mr. Raman, a 54-year-old man was brought to the emergency department with unconscious level and increased respiratory rate for the last 4 hours. He is having a history of uncontrolled diabetes mellitus past 15 years, as he was not following any medical advice from a physician.
He was on insulin therapy for 3 years, but he was not taking a regular dose of insulin. The patient’s relative is telling that he is also having to complain of weakness and decrease urine output for the last 2 days.
On General examination, the physician noted that Mr. Raman has the following signs and symptoms:
- Dryness of mouth.
- Pale & dry conjunctive
- Shrunken eyeball.
- Low volume pulse
- Tachypnea
- Tachycardia
- Very low blood pressure.
A doctor makes the admission to ICU and asked immediately for a blood investigation.
- Give an explanation for the altered consciousness condition and increase respiratory rate in this patient.
- Explain what metabolic effects and functional abnormalities can occur due to increased acetone levels in this patient.
- What is Diabetic ketoacidosis and explain the effect of acidosis on 02-0O2?
- What are the pathophysiological effects due to decrease urine output in this patient?
- Describe your findings on the patient’s Arterial Blood Gas (ABG) report.
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